SCOPe 2.05: Domain d2zdta_: 2zdt A:

Lineage for d2zdta_ (2zdt A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)

8. Domain d2zdta_: 2zdt A: [154400]
   automated match to d1jnka_
   complexed with 46c, gol

Details for d2zdta_

PDB Entry: 2zdt, 2 Å

PDB Description: Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor

PDB Compounds: (A:) Mitogen-activated protein kinase 10

SCOPe Domain Sequences for d2zdta_:

Sequence, based on SEQRES records:

>d2zdta_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyv
vtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcp
efmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidp
akrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmn

Sequence, based on observed residues (ATOM records):

>d2zdta_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglasfmmtpyvvtryy
rapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkk
lqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakris
vddalqhpyinvwydpaeveappprehtieewkeliykevmn

Timeline for d2zdta_:

• d2zdta_ first appeared in SCOP 1.75, called d2zdta1
  
• d2zdta_ appears in SCOPe 2.04
  
• d2zdta_ appears in SCOPe 2.06
  
• d2zdta_ appears in the current release, SCOPe 2.08