SCOPe 2.02: Domain d2zb0a_: 2zb0 A:

Lineage for d2zb0a_ (2zb0 A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)

8. Domain d2zb0a_: 2zb0 A: [154297]
   automated match to d1a9ua_
   complexed with gk3, gol

Details for d2zb0a_

PDB Entry: 2zb0, 2.1 Å

PDB Description: crystal structure of p38 in complex with biphenyl amide inhibitor

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2zb0a_:

Sequence; same for both SEQRES and ATOM records:

>d2zb0a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvppp

Timeline for d2zb0a_:

• d2zb0a_ first appeared in SCOP 1.75, called d2zb0a1
  
• d2zb0a_ appears in SCOPe 2.01
  
• d2zb0a_ appears in SCOPe 2.03
  
• d2zb0a_ appears in the current release, SCOPe 2.08