SCOPe 2.08: Domain d2z9ab_: 2z9a B:

Lineage for d2z9ab_ (2z9a B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.64: Saposin-like [47861] (2 superfamilies)
   5 helices; folded leaf, closed

4. Superfamily a.64.1: Saposin [47862] (5 families)
   Lipid-binding can promote conformational changes and oligomerisation in some members

5. Family a.64.1.1: NKL-like [47863] (4 proteins)

6. Protein Saposin C [89077] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89078] (11 PDB entries)

8. Domain d2z9ab_: 2z9a B: [154236]
   automated match to d1m12a_
   complexed with gol

Details for d2z9ab_

PDB Entry: 2z9a, 2.5 Å

PDB Description: Crystal Structure of Human Saposin C Dimer in Open Conformation

PDB Compounds: (B:) Proactivator polypeptide

SCOPe Domain Sequences for d2z9ab_:

Sequence; same for both SEQRES and ATOM records:

>d2z9ab_ a.64.1.1 (B:) Saposin C {Human (Homo sapiens) [TaxId: 9606]}
dvycevceflvkevtklidnnktekeildafdkmcsklpkslseecqevvdtygssilsi
lleevspelvcsmlhlcs

Timeline for d2z9ab_:

• d2z9ab_ first appeared in SCOP 1.75, called d2z9ab1
  
• d2z9ab_ appears in SCOPe 2.07