SCOPe 2.08: Domain d2z91c1: 2z91 C:114-212

Lineage for d2z91c1 (2z91 C:114-212)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (7 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88576] (391 PDB entries)
   Uniprot P01864 # GCAB_MOUSE Ig gamma-2A chain C region secreted form (B allele) ! Uniprot P01863 #GCAA_MOUSE Ig gamma-2A chain C region, A allele; 86% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form) ! Uniprot P01868 # GC1_MOUSE Ig gamma-1 chain C region secreted form ! Uniprot P01864 # GCAB_MOUSE (P01864) Ig gamma-2A chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! Uniprot P01863 # GCAA_MOUSE Ig gamma-2A chain C region, A allele ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01868 # ! GC1_MOUSE Ig gamma-1 chain C region secreted form

8. Domain d2z91c1: 2z91 C:114-212 [154222]
   Other proteins in same PDB: d2z91b1, d2z91b2, d2z91d1, d2z91d2
   automatically matched to d1fnsh2

Details for d2z91c1

PDB Entry: 2z91, 2.6 Å

PDB Description: Crystal structure of the Fab fragment of anti-ciguatoxin antibody 10C9

PDB Compounds: (C:) Anti-ciguatoxin antibody 10C9 Fab heavy chain

SCOPe Domain Sequences for d2z91c1:

Sequence, based on SEQRES records:

>d2z91c1 b.1.1.2 (C:114-212) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
akttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsd
lytlsssvtvpsstwpsetvtcnvahpasstkvdkkivp

Sequence, based on observed residues (ATOM records):

>d2z91c1 b.1.1.2 (C:114-212) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Mouse (Mus musculus) [TaxId: 10090]}
akttppsvyplapgmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsss
vtvpwpsetvtcnvahpasstkvdkkivp

Timeline for d2z91c1:

• d2z91c1 first appeared in SCOP 1.75
  
• d2z91c1 appears in SCOPe 2.07