Lineage for d2z8ca1 (2z8c A:984-1283)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2588247Protein Insulin receptor [56162] (1 species)
    PTK group; InsR subfamily; membrane spanning protein tyrosine kinase
  7. 2588248Species Human (Homo sapiens) [TaxId:9606] [56163] (18 PDB entries)
  8. 2588270Domain d2z8ca1: 2z8c A:984-1283 [154208]
    automatically matched to d1gaga_
    complexed with s91

Details for d2z8ca1

PDB Entry: 2z8c (more details), 3.25 Å

PDB Description: phosphorylated insulin receptor tyrosine kinase in complex with (4- {[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid
PDB Compounds: (A:) Insulin receptor

SCOPe Domain Sequences for d2z8ca1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2z8ca1 d.144.1.7 (A:984-1283) Insulin receptor {Human (Homo sapiens) [TaxId: 9606]}
fvpdewevsrekitllrelgqgsfgmvyegnardiikgeaetrvavktvnesaslrerie
flneasvmkgftchhvvrllgvvskgqptlvvmelmahgdlksylrslrpeaennpgrpp
ptlqemiqmaaeiadgmaylnakkfvhrdlaarncmvahdftvkigdfgmtrdiyetdyy
rkggkgllpvrwmapeslkdgvfttssdmwsfgvvlweitslaeqpyqglsneqvlkfvm
dggyldqpdncpervtdlmrmcwqfnpkmrptfleivnllkddlhpsfpevsffhseenk

SCOPe Domain Coordinates for d2z8ca1:

Click to download the PDB-style file with coordinates for d2z8ca1.
(The format of our PDB-style files is described here.)

Timeline for d2z8ca1: