SCOP 1.75: Domain d2z4oa1: 2z4o A:1-99

Lineage for d2z4oa1 (2z4o A:1-99)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (3 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (247 PDB entries)
   Uniprot P35963 57-155
   Uniprot P04587 69-167
   Uniprot P03366 69-167
   Uniprot P03367 69-167
   Uniprot P03368 69-167
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d2z4oa1: 2z4o A:1-99 [154159]
   automatically matched to d1fgcc_
   complexed with 065, act, cl, na; mutant

Details for d2z4oa1

PDB Entry: 2z4o, 1.6 Å

PDB Description: wild type hiv-1 protease with potent antiviral inhibitor grl-98065

PDB Compounds: (A:) Protease

SCOP Domain Sequences for d2z4oa1:

Sequence; same for both SEQRES and ATOM records:

>d2z4oa1 b.50.1.1 (A:1-99) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d2z4oa1:

• d2z4oa1 is new in SCOP 1.75
  
• d2z4oa1 is called d2z4oa_ in SCOPe 2.01
  
• d2z4oa1 appears in the current release, SCOPe 2.08, called d2z4oa_