SCOPe 2.05: Domain d2vsta_: 2vst A:

Lineage for d2vsta_ (2vst A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (138 PDB entries)

8. Domain d2vsta_: 2vst A: [153531]
   automated match to d1wm0x_
   protein/DNA complex; complexed with 243

Details for d2vsta_

PDB Entry: 2vst, 2.35 Å

PDB Description: hPPARgamma Ligand binding domain in complex with 13-(S)-HODE

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d2vsta_:

Sequence, based on SEQRES records:

>d2vsta_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkik
fkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvh
eiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsd
laifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlr
qivtehvqllqvikktetdmslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d2vsta_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkik
evairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmn
kdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsg
drpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqv
ikktetdmslhpllqeiykd

Timeline for d2vsta_:

• d2vsta_ first appeared in SCOP 1.75, called d2vsta1
  
• d2vsta_ appears in SCOPe 2.04
  
• d2vsta_ appears in SCOPe 2.06
  
• d2vsta_ appears in the current release, SCOPe 2.08