Lineage for d2vlef1 (2vle F:7-500)

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 844892Fold c.82: ALDH-like [53719] (1 superfamily)
    consists of two similar domains with 3 layers (a/b/a) each; duplication
    core: parallel beta-sheet of 5 strands, order 32145
  4. 844893Superfamily c.82.1: ALDH-like [53720] (2 families) (S)
    binds NAD differently from other NAD(P)-dependent oxidoreductases
  5. 844894Family c.82.1.1: ALDH-like [53721] (5 proteins)
  6. 844901Protein Aldehyde reductase (dehydrogenase), ALDH [53722] (9 species)
  7. 844925Species Human (Homo sapiens), mitochondrial [TaxId:9606] [53726] (10 PDB entries)
    Uniprot P05091
  8. 844963Domain d2vlef1: 2vle F:7-500 [153274]
    automatically matched to d1o01c_
    complexed with dzn

Details for d2vlef1

PDB Entry: 2vle (more details), 2.4 Å

PDB Description: the structure of daidzin, a naturally occurring anti alcohol-addiction agent, in complex with human mitochondrial aldehyde dehydrogenase
PDB Compounds: (F:) aldehyde dehydrogenase, mitochondrial

SCOP Domain Sequences for d2vlef1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2vlef1 c.82.1.1 (F:7-500) Aldehyde reductase (dehydrogenase), ALDH {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
avpapnqqpevfcnqifinnewhdavsrktfptvnpstgevicqvaegdkedvdkavkaa
raafqlgspwrrmdashrgrllnrladlierdrtylaaletldngkpyvisylvdldmvl
kclryyagwadkyhgktipidgdffsytrhepvgvcgqiipwnfpllmqawklgpalatg
nvvvmkvaeqtpltalyvanlikeagfppgvvnivpgfgptagaaiashedvdkvaftgs
teigrviqvaagssnlkrvtlelggkspniimsdadmdwaveqahfalffnqgqcccags
rtfvqediydefversvaraksrvvgnpfdskteqgpqvdetqfkkilgyintgkqegak
llcgggiaadrgyfiqptvfgdvqdgmtiakeeifgpvmqilkfktieevvgrannstyg
laaavftkdldkanylsqalqagtvwvncydvfgaqspfggykmsgsgrelgeyglqayt
evktvtvkvpqkns

SCOP Domain Coordinates for d2vlef1:

Click to download the PDB-style file with coordinates for d2vlef1.
(The format of our PDB-style files is described here.)

Timeline for d2vlef1: