Lineage for d2viwa1 (2viw A:16-244)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 802045Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 802046Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 802237Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)
  6. 803442Protein Urokinase-type plasminogen activator (LMW U-PA), catalytic domain [50586] (1 species)
  7. 803443Species Human (Homo sapiens) [TaxId:9606] [50587] (49 PDB entries)
    Uniprot P00749 156-178,179-424
  8. 803481Domain d2viwa1: 2viw A:16-244 [153175]
    automatically matched to d1ejna_
    complexed with act, d56; mutant

Details for d2viwa1

PDB Entry: 2viw (more details), 2.05 Å

PDB Description: fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator
PDB Compounds: (A:) urokinase-type plasminogen activator chain b

SCOP Domain Sequences for d2viwa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2viwa1 b.47.1.2 (A:16-244) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}

SCOP Domain Coordinates for d2viwa1:

Click to download the PDB-style file with coordinates for d2viwa1.
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Timeline for d2viwa1: