SCOPe 2.08: Domain d2v8xa1: 2v8x A:32-217

Lineage for d2v8xa1 (2v8x A:32-217)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.86: eIF4e-like [55417] (1 superfamily)
   beta(2)-alpha-beta(2)-alpha-beta(2)-alpha-beta-2; 2 layers: alpha/beta; antiparallel sheet: 21356478

4. Superfamily d.86.1: eIF4e-like [55418] (3 families)

5. Family d.86.1.1: Translation initiation factor eIF4e [55419] (1 protein)
   automatically mapped to Pfam PF01652

6. Protein Translation initiation factor eIF4e [55420] (3 species)
   messenger RNA 5' cap-binding protein

7. Species Human (Homo sapiens) [TaxId:9606] [160542] (16 PDB entries)

8. Domain d2v8xa1: 2v8x A:32-217 [152787]
   automatically matched to d1ipba_
   complexed with mgq

Details for d2v8xa1

PDB Entry: 2v8x, 2.3 Å

PDB Description: crystallographic and mass spectrometric characterisation of eif4e with n7-cap derivatives

PDB Compounds: (A:) eukaryotic translation initiation factor 4e

SCOPe Domain Sequences for d2v8xa1:

Sequence, based on SEQRES records:

>d2v8xa1 d.86.1.1 (A:32-217) Translation initiation factor eIF4e {Human (Homo sapiens) [TaxId: 9606]}
ehyikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdy
slfkdgiepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcg
avvnvrakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtatksgstt
knrfvv

Sequence, based on observed residues (ATOM records):

>d2v8xa1 d.86.1.1 (A:32-217) Translation initiation factor eIF4e {Human (Homo sapiens) [TaxId: 9606]}
ehyikhplqnrwalwffkndksktwqanlrliskfdtvedfwalynhiqlssnlmpgcdy
slfkdgiepmwedeknkrggrwlitlnkqqrrsdldrfwletllcligesfddysddvcg
avvnvrakgdkiaiwttecenreavthigrvykerlglppkivigyqshadtattknrfv
v

Timeline for d2v8xa1:

• d2v8xa1 first appeared in SCOP 1.75
  
• d2v8xa1 appears in SCOPe 2.07