SCOPe 2.08: Domain d2v64c2: 2v64 C:2-205

Lineage for d2v64c2 (2v64 C:2-205)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.135: The spindle assembly checkpoint protein mad2 [56018] (1 superfamily)
   core: alpha(2)-beta(2)-alpha-beta; mixed sheet: order 213

4. Superfamily d.135.1: The spindle assembly checkpoint protein mad2 [56019] (2 families)
   N- and C-termini undergo large conformational rearrangement upon ligand binding
   automatically mapped to Pfam PF02301

5. Family d.135.1.1: The spindle assembly checkpoint protein mad2 [56020] (2 proteins)

6. Protein automated matches [190416] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187293] (2 PDB entries)

8. Domain d2v64c2: 2v64 C:2-205 [152618]
   Other proteins in same PDB: d2v64a3, d2v64c3, d2v64f3
   automated match to d1s2ha_

Details for d2v64c2

PDB Entry: 2v64, 2.9 Å

PDB Description: crystallographic structure of the conformational dimer of the spindle assembly checkpoint protein mad2.

PDB Compounds: (C:) mitotic spindle assembly checkpoint protein mad2a

SCOPe Domain Sequences for d2v64c2:

Sequence; same for both SEQRES and ATOM records:

>d2v64c2 d.135.1.1 (C:2-205) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alqlsreqgitlrgsaeivaeffsfginsilyqrgiypsetftrvqkygltllvttdlel
ikylnnvveqlkdwlykcsvqklvvvisniesgevlerwqfdiecdktakddsapreksq
kaiqdeirsvirqitatvtflpllevscsfdlliytdkdlvvpekweesgpqfitnseev
rlrsftttihkvnsmvaykipvnd

Timeline for d2v64c2:

• d2v64c2 first appeared in SCOP 1.75, called d2v64c1
  
• d2v64c2 appears in SCOPe 2.07