SCOPe 2.06: Domain d2v3ka_: 2v3k A:

Lineage for d2v3ka_ (2v3k A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (9 families)
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures

5. Family c.116.1.6: EMG1/NEP1-like [159513] (3 proteins)
   Pfam PF03587; structurally most similar to the AF1056-like family, but more decorated

6. Protein Essential for mitotic growth 1, EMG1 [159516] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [159517] (2 PDB entries)
   Uniprot Q06287 23-251

8. Domain d2v3ka_: 2v3k A: [152460]
   automated match to d2v3ja1
   complexed with sam, so4

Details for d2v3ka_

PDB Entry: 2v3k, 2 Å

PDB Description: the yeast ribosome synthesis factor emg1 alpha beta knot fold methyltransferase

PDB Compounds: (A:) essential for mitotic growth 1

SCOPe Domain Sequences for d2v3ka_:

Sequence, based on SEQRES records:

>d2v3ka_ c.116.1.6 (A:) Essential for mitotic growth 1, EMG1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pqappvltskdkitkrmivvlamaslethkissngpggdkyvllncddhqgllkkmgrdi
searpdithqclltlldspinkagklqvyiqtsrgilievnptvriprtfkrfsglmvql
lhklsirsvnseekllkviknpitdhlptkcrkvtlsfdapvirvqdyiekldddesicv
fvgamargkdnfadeyvdekvglsnyplsasvacskfchgaedawni

Sequence, based on observed residues (ATOM records):

>d2v3ka_ c.116.1.6 (A:) Essential for mitotic growth 1, EMG1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pqappvltskdkitkrmivvlamaslethkiyvllncddhqgllkkmgrdisearpdith
qclltlldspinkagklqvyiqtsrgilievnptvriprtfkrfsglmvqllhklsirsv
nseekllkviknpitdhlptkcrkvtlsfdapvirvqdyiekldddesicvfvgamargk
dnfadeyvdekvglsnyplsasvacskfchgaedawni

Timeline for d2v3ka_:

• d2v3ka_ first appeared in SCOP 1.75, called d2v3ka1
  
• d2v3ka_ appears in SCOPe 2.05
  
• d2v3ka_ appears in SCOPe 2.07
  
• d2v3ka_ appears in the current release, SCOPe 2.08