SCOPe 2.08: Domain d2uweb2: 2uwe B:1-99

Lineage for d2uweb2 (2uwe B:1-99)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (480 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d2uweb2: 2uwe B:1-99 [152208]
   Other proteins in same PDB: d2uwea1, d2uwea2, d2uweb3, d2uwee1, d2uwee2, d2uwef1, d2uwef2, d2uweh1, d2uweh2, d2uwei3, d2uwel1, d2uwel2, d2uwem1, d2uwem2
   automated match to d1a9bb_
   mutant

Details for d2uweb2

PDB Entry: 2uwe, 2.4 Å

PDB Description: large cdr3a loop alteration as a function of mhc mutation

PDB Compounds: (B:) Beta-2-microglobulin

SCOPe Domain Sequences for d2uweb2:

Sequence; same for both SEQRES and ATOM records:

>d2uweb2 b.1.1.2 (B:1-99) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d2uweb2:

• d2uweb2 first appeared in SCOP 1.75, called d2uweb1
  
• d2uweb2 appears in SCOPe 2.07