Lineage for d2uwea2 (2uwe A:1-181)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 856282Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
    dimeric
  4. 856283Superfamily d.19.1: MHC antigen-recognition domain [54452] (1 family) (S)
  5. 856284Family d.19.1.1: MHC antigen-recognition domain [54453] (12 proteins)
  6. 856331Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (27 species)
  7. 856344Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (76 PDB entries)
    Uniprot P01892 25-298
  8. 856413Domain d2uwea2: 2uwe A:1-181 [152207]
    Other proteins in same PDB: d2uwea1, d2uweb1, d2uwee1, d2uwee2, d2uwef1, d2uwef2, d2uweh1, d2uwei1, d2uwel1, d2uwel2, d2uwem1, d2uwem2
    automatically matched to d1akja2
    mutant

Details for d2uwea2

PDB Entry: 2uwe (more details), 2.4 Å

PDB Description: large cdr3a loop alteration as a function of mhc mutation
PDB Compounds: (A:) HLA class I histocompatibility antigen, A-2 alpha chain

SCOP Domain Sequences for d2uwea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2uwea2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-A2.1 [TaxId: 9606]}
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegacvewlrrylengketlq
r

SCOP Domain Coordinates for d2uwea2:

Click to download the PDB-style file with coordinates for d2uwea2.
(The format of our PDB-style files is described here.)

Timeline for d2uwea2: