Lineage for d2roca2 (2roc A:152-308)

  1. Root: SCOPe 2.06
  2. 2250849Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)
  3. 2250850Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 2250926Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 2250927Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 2251038Protein EAT/MCL-1 (Myeloid cell leukemia sequence 1) [118212] (3 species)
  7. 2251041Species Mouse (Mus musculus) [TaxId:10090] [118213] (5 PDB entries)
    Uniprot P97287 152-308
  8. 2251044Domain d2roca2: 2roc A:152-308 [152176]
    Other proteins in same PDB: d2roca3
    automated match to d2roda1

Details for d2roca2

PDB Entry: 2roc (more details)

PDB Description: solution structure of mcl-1 complexed with puma
PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1 homolog

SCOPe Domain Sequences for d2roca2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2roca2 f.1.4.1 (A:152-308) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Mouse (Mus musculus) [TaxId: 10090]}
eddlyrqsleiisrylreqatgskdskplgeagaagrraletlrrvgdgvqrnhetafqg
mlrkldiknegdvksfsrvmvhvfkdgvtnwgrivtlisfgafvakhlksvnqesfiepl
aetitdvlvrtkrdwlvkqrgwdgfveffhvqdlegg

SCOPe Domain Coordinates for d2roca2:

Click to download the PDB-style file with coordinates for d2roca2.
(The format of our PDB-style files is described here.)

Timeline for d2roca2: