SCOPe 2.08: Domain d2rnxa2: 2rnx A:719-832

Lineage for d2rnxa2 (2rnx A:719-832)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.1: Bromodomain [47371] (6 proteins)

6. Protein P300/CAF histone acetyltransferase bromodomain [47375] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47376] (8 PDB entries)

8. Domain d2rnxa2: 2rnx A:719-832 [152174]
   Other proteins in same PDB: d2rnxa3
   automated match to d2rnxa1
   protein/DNA complex

Details for d2rnxa2

PDB Entry: 2rnx

PDB Description: the structural basis for site-specific lysine-acetylated histone recognition by the bromodomains of the human transcriptional co- activators pcaf and cbp

PDB Compounds: (A:) Histone acetyltransferase PCAF

SCOPe Domain Sequences for d2rnxa2:

Sequence; same for both SEQRES and ATOM records:

>d2rnxa2 a.29.2.1 (A:719-832) P300/CAF histone acetyltransferase bromodomain {Human (Homo sapiens) [TaxId: 9606]}
skeprdpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlktmserlk
nryyvskklfmadlqrvftnckeynppeseyykcanilekfffskikeaglidk

Timeline for d2rnxa2:

• d2rnxa2 first appeared in SCOP 1.75, called d2rnxa1
  
• d2rnxa2 appears in SCOPe 2.07