Lineage for d2rg6a_ (2rg6 A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1221011Protein MAP kinase p38 [56129] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 1221012Species Human (Homo sapiens) [TaxId:9606] [56130] (124 PDB entries)
  8. 1221017Domain d2rg6a_: 2rg6 A: [152007]
    automated match to d1a9ua_
    complexed with 287

Details for d2rg6a_

PDB Entry: 2rg6 (more details), 1.72 Å

PDB Description: Phenylalanine pyrrolotriazine p38 alpha map kinase inhibitor compound 11J
PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2rg6a_:

Sequence, based on SEQRES records: (download)

>d2rg6a_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvppp

Sequence, based on observed residues (ATOM records): (download)

>d2rg6a_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvggsvcaafdtktglrvavkklsrpfqsiihakr
tyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhv
qfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglaratrwyrapeimlnw
mhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarn
yiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpdde
pvadpydqsfesrdllidewksltydevisfvppp

SCOPe Domain Coordinates for d2rg6a_:

Click to download the PDB-style file with coordinates for d2rg6a_.
(The format of our PDB-style files is described here.)

Timeline for d2rg6a_: