SCOP 1.75: Domain d2rewa1: 2rew A:199-467

Lineage for d2rewa1 (2rew A:199-467)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69110] (5 PDB entries)

8. Domain d2rewa1: 2rew A:199-467 [151991]
   automatically matched to d1i7ga_
   complexed with cpq, rew

Details for d2rewa1

PDB Entry: 2rew, 2.35 Å

PDB Description: crystal structure of pparalpha ligand binding domain with bms-631707

PDB Compounds: (A:) Peroxisome proliferator-activated receptor alpha

SCOP Domain Sequences for d2rewa1:

Sequence, based on SEQRES records:

>d2rewa1 a.123.1.1 (A:199-467) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
etadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvakl
vangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaif
amlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislf
vaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvt
ehaqlvqiikktesdaalhpllqeiyrdm

Sequence, based on observed residues (ATOM records):

>d2rewa1 a.123.1.1 (A:199-467) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
etadlkslakriyeaylknfnmnkvkarvilsgppfvihdmetlcmaektlqnkeaevri
fhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifamlssvmnkdgmlv
aygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaaiiccgdrpgll
nvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvtehaqlvqiikktes
daalhpllqeiyrdm

Timeline for d2rewa1:

• d2rewa1 is new in SCOP 1.75
  
• d2rewa1 is called d2rewa_ in SCOPe 2.01
  
• d2rewa1 appears in the current release, SCOPe 2.08, called d2rewa_