SCOPe 2.08: Domain d2rcwa1: 2rcw A:1-137

Lineage for d2rcwa1 (2rcw A:1-137)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
   core: 4 helices: bundle; unusual topology

4. Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families)
   duplication: consists of 2 helix-loop-helix structural repeats
   automatically mapped to Pfam PF02877

5. Family a.41.1.1: Domain of poly(ADP-ribose) polymerase [47588] (1 protein)

6. Protein Domain of poly(ADP-ribose) polymerase [47589] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101198] (8 PDB entries)
   Uniprot P09874 661-1010

8. Domain d2rcwa1: 2rcw A:1-137 [151911]
   Other proteins in same PDB: d2rcwa2
   automated match to d1uk1a1
   protein/DNA complex; complexed with aai

Details for d2rcwa1

PDB Entry: 2rcw, 2.8 Å

PDB Description: PARP complexed with A620223

PDB Compounds: (A:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d2rcwa1:

Sequence; same for both SEQRES and ATOM records:

>d2rcwa1 a.41.1.1 (A:1-137) Domain of poly(ADP-ribose) polymerase {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgssdsqildlsnrfytliphdfgmkkppllnnadsvqakvemldnlldievaysllrgg
sddsskdpidvnyeklk

Timeline for d2rcwa1:

• d2rcwa1 first appeared in SCOP 1.75
  
• d2rcwa1 appears in SCOPe 2.07