SCOPe 2.05: Domain d2r85a2: 2r85 A:100-334

Lineage for d2r85a2 (2r85 A:100-334)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (10 families)

5. Family d.142.1.9: PurP ATP-binding domain-like [160804] (1 protein)
   Pfam PF06973; DUF1297

6. Protein 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase PurP [160805] (3 species)

7. Species Pyrococcus furiosus [TaxId:2261] [160808] (4 PDB entries)
   Uniprot Q8U0R7 100-334

8. Domain d2r85a2: 2r85 A:100-334 [151677]
   Other proteins in same PDB: d2r85a1, d2r85b1
   automated match to d2r84a2
   complexed with amp, cl, mpd, na

Details for d2r85a2

PDB Entry: 2r85, 1.7 Å

PDB Description: crystal structure of purp from pyrococcus furiosus complexed with amp

PDB Compounds: (A:) PurP protein PF1517

SCOPe Domain Sequences for d2r85a2:

Sequence, based on SEQRES records:

>d2r85a2 d.142.1.9 (A:100-334) 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase PurP {Pyrococcus furiosus [TaxId: 2261]}
drnlerkwlkkagirvpevyedpddiekpvivkphgakggkgyflakdpedfwrkaekfl
gikrkedlkniqiqeyvlgvpvyphyfyskvreelelmsidrryesnvdaigripakdql
efdmditytvignipivlresllmdvieagervvkaaeelmgglwgpfclegvftpdlef
vvfeisarivagtnifvngspytwlrydrpvstgrriameireaiendmlekvlt

Sequence, based on observed residues (ATOM records):

>d2r85a2 d.142.1.9 (A:100-334) 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase PurP {Pyrococcus furiosus [TaxId: 2261]}
drnlerkwlkkagirvpevyedpddiekpvivkphgkgyflakdpedfwrkaekflgikr
kedlkniqiqeyvlgvpvyphyfyskvreelelmsidrryesnvdaigripakdqlefdm
ditytvignipivlresllmdvieagervvkaaeelmgglwgpfclegvftpdlefvvfe
isarivagtnifvngspytwlrydrpvstgrriameireaiendmlekvlt

Timeline for d2r85a2:

• d2r85a2 first appeared in SCOP 1.75
  
• d2r85a2 appears in SCOPe 2.04
  
• d2r85a2 appears in SCOPe 2.06
  
• d2r85a2 appears in the current release, SCOPe 2.08