SCOPe 2.06: Domain d2r84a1: 2r84 A:1-99

Lineage for d2r84a1 (2r84 A:1-99)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.30: PreATP-grasp domain [52439] (1 superfamily)
   3 layers: a/b/a; parallel or mixed beta-sheet of 4 to 6 strands
   possible rudiment form of Rossmann-fold domain

4. Superfamily c.30.1: PreATP-grasp domain [52440] (10 families)
   precedes the ATP-grasp domain common to all superfamily members, can contain a substrate-binding function

5. Family c.30.1.8: PurP N-terminal domain-like [159526] (1 protein)
   Pfam PF06849; DUF1246

6. Protein 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase PurP [159527] (3 species)

7. Species Pyrococcus furiosus [TaxId:2261] [159528] (4 PDB entries)
   Uniprot Q8U0R7 1-99

8. Domain d2r84a1: 2r84 A:1-99 [151672]
   Other proteins in same PDB: d2r84a2, d2r84b2
   complexed with amp, amz, cl, mpd, na

Details for d2r84a1

PDB Entry: 2r84, 1.9 Å

PDB Description: crystal structure of purp from pyrococcus furiosus complexed with amp and aicar

PDB Compounds: (A:) PurP protein PF1517

SCOPe Domain Sequences for d2r84a1:

Sequence; same for both SEQRES and ATOM records:

>d2r84a1 c.30.1.8 (A:1-99) 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase PurP {Pyrococcus furiosus [TaxId: 2261]}
mkvriatyashsalqilkgakdegfetiafgsskvkplytkyfpvadyfieekypeeell
nlnavvvptgsfvahlgielvenmkvpyfgnkrvlrwes

Timeline for d2r84a1:

• d2r84a1 first appeared in SCOP 1.75
  
• d2r84a1 appears in SCOPe 2.05
  
• d2r84a1 appears in SCOPe 2.07
  
• d2r84a1 appears in the current release, SCOPe 2.08