SCOPe 2.06: Domain d2r7gc1: 2r7g C:380-579

Lineage for d2r7gc1 (2r7g C:380-579)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (4 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.3: Retinoblastoma tumor suppressor domains [47969] (1 protein)

6. Protein Retinoblastoma tumor suppressor domains [47970] (1 species)
   contains an additional C-terminal helix

7. Species Human (Homo sapiens) [TaxId:9606] [47971] (7 PDB entries)

8. Domain d2r7gc1: 2r7g C:380-579 [151639]
   automated match to d1n4ma1
   complexed with so4

Details for d2r7gc1

PDB Entry: 2r7g, 1.67 Å

PDB Description: structure of the retinoblastoma protein pocket domain in complex with adenovirus e1a cr1 domain

PDB Compounds: (C:) Retinoblastoma-associated protein

SCOPe Domain Sequences for d2r7gc1:

Sequence, based on SEQRES records:

>d2r7gc1 a.74.1.3 (C:380-579) Retinoblastoma tumor suppressor domains {Human (Homo sapiens) [TaxId: 9606]}
ntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfakavgqgcv
eigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacalevvmatys
rstsqnldsgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhlercehrime
slawlsdsplfdlikqskdr

Sequence, based on observed residues (ATOM records):

>d2r7gc1 a.74.1.3 (C:380-579) Retinoblastoma tumor suppressor domains {Human (Homo sapiens) [TaxId: 9606]}
ntiqqlmmilnsasdqpsenlisyfnnctvnpkesilkrvkdigyifkekfakavgqgcv
eigsqryklgvrlyyrvmesmlkseeerlsiqnfskllndnifhmsllacalevvmatys
rstgtdlsfpwilnvlnlkafdfykviesfikaegnltremikhlercehrimeslawls
dsplfdlikqskdr

Timeline for d2r7gc1:

• d2r7gc1 first appeared in SCOP 1.75
  
• d2r7gc1 appears in SCOPe 2.05
  
• d2r7gc1 appears in SCOPe 2.07
  
• d2r7gc1 appears in the current release, SCOPe 2.08