SCOP 1.75: Domain d2r2wu1: 2r2w U:16-244

Lineage for d2r2wu1 (2r2w U:16-244)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Urokinase-type plasminogen activator (LMW U-PA), catalytic domain [50586] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50587] (49 PDB entries)
   Uniprot P00749 156-178,179-424

8. Domain d2r2wu1: 2r2w U:16-244 [151542]
   automatically matched to d1ejna_
   complexed with 4pg, so4; mutant

Details for d2r2wu1

PDB Entry: 2r2w, 2.01 Å

PDB Description: urokinase plasminogen activator b-chain-gppe complex

PDB Compounds: (U:) Plasminogen activator, urokinase

SCOP Domain Sequences for d2r2wu1:

Sequence; same for both SEQRES and ATOM records:

>d2r2wu1 b.47.1.2 (U:16-244) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
slpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtke

Timeline for d2r2wu1:

• d2r2wu1 is new in SCOP 1.75
  
• d2r2wu1 appears in SCOPe 2.01
  
• d2r2wu1 appears in the current release, SCOPe 2.08, called d2r2wu_