SCOP 1.75: Domain d2r0na2: 2r0n A:3-238

Lineage for d2r0na2 (2r0n A:3-238)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.6: Acyl-CoA dehydrogenase NM domain-like [56644] (1 superfamily)
   2 domains: (1) all-alpha: 5 helices; (2) contains an open beta-sheet barrel: n*=5, S*=8; complex topology

4. Superfamily e.6.1: Acyl-CoA dehydrogenase NM domain-like [56645] (2 families)
   flavoprotein: binds FAD; constituent families differ in the numbers of C-terminal domains (four-helical bundles)

5. Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains [56646] (9 proteins)

6. Protein Glutaryl-CoA dehydrogenase GCDH [111293] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [111294] (4 PDB entries)
   Uniprot Q92947

8. Domain d2r0na2: 2r0n A:3-238 [151507]
   Other proteins in same PDB: d2r0na1
   automatically matched to d1siqa2
   complexed with fad, tgc; mutant

Details for d2r0na2

PDB Entry: 2r0n, 2.3 Å

PDB Description: The effect of a Glu370Asp mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate

PDB Compounds: (A:) Glutaryl-CoA dehydrogenase

SCOP Domain Sequences for d2r0na2:

Sequence; same for both SEQRES and ATOM records:

>d2r0na2 e.6.1.1 (A:3-238) Glutaryl-CoA dehydrogenase GCDH {Human (Homo sapiens) [TaxId: 9606]}
efdwqdplvleeqlttdeilirdtfrtycqerlmprillanrnevfhreiisemgelgvl
gptikgygcagvssvaygllarelervdsgyrsamsvqsslvmhpiyaygseeqrqkylp
qlakgellgcfgltepnsgsdpssmetrahynssnksytlngtktwitnspmadlfvvwa
rcedgcirgfllekgmrglsapriqgkfslrasatgmiimdgvevpeenvlpgass

Timeline for d2r0na2:

• d2r0na2 is new in SCOP 1.75
  
• d2r0na2 appears in SCOPe 2.01
  
• d2r0na2 appears in the current release, SCOPe 2.08