SCOP 1.75: Domain d2qyna1: 2qyn A:86-411

Lineage for d2qyna1 (2qyn A:86-411)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (22 PDB entries)
   Uniprot Q08499 388-713

8. Domain d2qyna1: 2qyn A:86-411 [151475]
   automatically matched to d1oyna_
   complexed with mg, npv, zn

Details for d2qyna1

PDB Entry: 2qyn, 1.57 Å

PDB Description: Crystal structure of PDE4D2 in complex with inhibitor NPV

PDB Compounds: (A:) cAMP-specific 3',5'-cyclic phosphodiesterase 4D

SCOP Domain Sequences for d2qyna1:

Sequence; same for both SEQRES and ATOM records:

>d2qyna1 a.211.1.2 (A:86-411) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
teqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlity
lmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhp
gvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvi
divlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkp
lqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwa
dlvhpdaqdildtlednrewyqstip

Timeline for d2qyna1:

• d2qyna1 is new in SCOP 1.75
  
• d2qyna1 is called d2qyna_ in SCOPe 2.01
  
• d2qyna1 appears in the current release, SCOPe 2.08, called d2qyna_