Lineage for d2qp8a_ (2qp8 A:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 955287Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 955288Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 956278Family b.50.1.2: Pepsin-like [50646] (11 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 956335Protein beta-secretase (memapsin) [50671] (1 species)
  7. 956336Species Human (Homo sapiens) [TaxId:9606] [50672] (117 PDB entries)
    Uniprot P56817 58-446 ! Uniprot P56817 60-447
  8. 956337Domain d2qp8a_: 2qp8 A: [151197]
    automated match to d1fkna_
    complexed with sc7, tar

Details for d2qp8a_

PDB Entry: 2qp8 (more details), 1.5 Å

PDB Description: structure of bace bound to sch734723
PDB Compounds: (A:) Beta-secretase 1

SCOPe Domain Sequences for d2qp8a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2qp8a_ b.50.1.2 (A:) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2qp8a_:

Click to download the PDB-style file with coordinates for d2qp8a_.
(The format of our PDB-style files is described here.)

Timeline for d2qp8a_: