SCOPe 2.06: Domain d2qnqb_: 2qnq B:

Lineage for d2qnqb_ (2qnq B:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (476 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d2qnqb_: 2qnq B: [150952]
   automated match to d1ajva_
   protein/DNA complex; protein/RNA complex; complexed with cl, qn3

Details for d2qnqb_

PDB Entry: 2qnq, 2.3 Å

PDB Description: HIV-1 Protease in complex with a chloro decorated pyrrolidine-based inhibitor

PDB Compounds: (B:) Gag-Pol polyprotein (Pr160Gag-Pol)

SCOPe Domain Sequences for d2qnqb_:

Sequence; same for both SEQRES and ATOM records:

>d2qnqb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d2qnqb_:

• d2qnqb_ first appeared in SCOP 1.75, called d2qnqb1
  
• d2qnqb_ appears in SCOPe 2.05
  
• d2qnqb_ appears in SCOPe 2.07
  
• d2qnqb_ appears in the current release, SCOPe 2.08