Lineage for d2qk5a2 (2qk5 A:55-447)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2060177Family b.50.1.2: Pepsin-like [50646] (11 protein domains)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2060235Protein beta-secretase (memapsin) [50671] (1 species)
  7. 2060236Species Human (Homo sapiens) [TaxId:9606] [50672] (275 PDB entries)
    Uniprot P56817 58-446 ! Uniprot P56817 60-447
  8. 2060443Domain d2qk5a2: 2qk5 A:55-447 [150837]
    Other proteins in same PDB: d2qk5a3
    automated match to d1fkna_
    complexed with cs5

Details for d2qk5a2

PDB Entry: 2qk5 (more details), 2.2 Å

PDB Description: Structure of BACE1 bound to SCH626485
PDB Compounds: (A:) Beta-secretase 1

SCOPe Domain Sequences for d2qk5a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2qk5a2 b.50.1.2 (A:55-447) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2qk5a2:

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Timeline for d2qk5a2:

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