SCOPe 2.05: Domain d2qjba_: 2qjb A:

Lineage for d2qjba_ (2qjb A:)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57517] (13 PDB entries)

8. Domain d2qjba_: 2qjb A: [150827]
   Other proteins in same PDB: d2qjbc_, d2qjbd_
   automated match to d3bmpa_
   complexed with cl

Details for d2qjba_

PDB Entry: 2qjb, 2.5 Å

PDB Description: crystal structure analysis of bmp-2 in complex with bmpr-ia variant ia/ib

PDB Compounds: (A:) Bone morphogenetic protein 2

SCOPe Domain Sequences for d2qjba_:

Sequence; same for both SEQRES and ATOM records:

>d2qjba_ g.17.1.2 (A:) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

Timeline for d2qjba_:

• d2qjba_ first appeared in SCOP 1.75, called d2qjba1
  
• d2qjba_ appears in SCOPe 2.04
  
• d2qjba_ appears in SCOPe 2.06
  
• d2qjba_ appears in the current release, SCOPe 2.08