Lineage for d2qhma1 (2qhm A:2-276)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874505Protein Cell cycle checkpoint kinase chk1 [64404] (1 species)
    CaMK group; CAMKL subfamily; serine/threonine kinase
  7. 874506Species Human (Homo sapiens) [TaxId:9606] [64405] (35 PDB entries)
  8. 874520Domain d2qhma1: 2qhm A:2-276 [150788]
    automatically matched to d1ia8a_
    complexed with 7cs

Details for d2qhma1

PDB Entry: 2qhm (more details), 2 Å

PDB Description: crystal structure of Chek1 in complex with inhibitor 2a
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOP Domain Sequences for d2qhma1:

Sequence, based on SEQRES records: (download)

>d2qhma1 d.144.1.7 (A:2-276) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
avpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkm
lnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvyl
hgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkr
refhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplal
lhkilvenpsaritipdikkdrwynkplkkgakrp

Sequence, based on observed residues (ATOM records): (download)

>d2qhma1 d.144.1.7 (A:2-276) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
avpfvedwdlvqtlggevqlavnrvteeavavkivdmknikkeicinkmlnhenvvkfyg
hrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdik
penlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvw
scgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsa
ritipdikkdrwynkplkkgakrp

SCOP Domain Coordinates for d2qhma1:

Click to download the PDB-style file with coordinates for d2qhma1.
(The format of our PDB-style files is described here.)

Timeline for d2qhma1: