SCOPe 2.06: Domain d2qfaa_: 2qfa A:

Lineage for d2qfaa_ (2qfa A:)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.52: Inhibitor of apoptosis (IAP) repeat [57923] (1 superfamily)
   metal(zinc)-bound alpha+beta fold

4. Superfamily g.52.1: Inhibitor of apoptosis (IAP) repeat [57924] (2 families)

5. Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat [57925] (7 proteins)

6. Protein Anti-apoptotic protein survivin [57930] (2 species)
   contains a long alpha-helix after the common fold

7. Species Human (Homo sapiens) [TaxId:9606] [57931] (9 PDB entries)

8. Domain d2qfaa_: 2qfa A: [150733]
   automated match to d1e31b_
   complexed with mes, zn

Details for d2qfaa_

PDB Entry: 2qfa, 1.4 Å

PDB Description: Crystal structure of a Survivin-Borealin-INCENP core complex

PDB Compounds: (A:) Baculoviral IAP repeat-containing protein 5

SCOPe Domain Sequences for d2qfaa_:

Sequence; same for both SEQRES and ATOM records:

>d2qfaa_ g.52.1.1 (A:) Anti-apoptotic protein survivin {Human (Homo sapiens) [TaxId: 9606]}
tlppawqpflkdhristfknwpflegcactpermaeagfihcptenepdlaqcffcfkel
egwepdddpieehkkhssgcaflsvkkqfeeltlgeflkldreraknkiaketnnkkkef
eetakkvrraieqlaam

Timeline for d2qfaa_:

• d2qfaa_ first appeared in SCOP 1.75, called d2qfaa1
  
• d2qfaa_ appears in SCOPe 2.05
  
• d2qfaa_ appears in SCOPe 2.07
  
• d2qfaa_ appears in the current release, SCOPe 2.08