Lineage for d2q80e1 (2q80 E:6-295)

  1. Root: SCOP 1.75
  2. 758332Class a: All alpha proteins [46456] (284 folds)
  3. 777410Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 777411Superfamily a.128.1: Terpenoid synthases [48576] (5 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 777412Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (3 proteins)
  6. 777428Protein Geranylgeranyl pyrophosphate synthetase [158813] (1 species)
  7. 777429Species Human (Homo sapiens) [TaxId:9606] [158814] (1 PDB entry)
    Uniprot O95749 6-296
  8. 777434Domain d2q80e1: 2q80 E:6-295 [150116]
    automatically matched to 2Q80 A:6-296
    complexed with grg, mg

Details for d2q80e1

PDB Entry: 2q80 (more details), 2.7 Å

PDB Description: Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP
PDB Compounds: (E:) Geranylgeranyl pyrophosphate synthetase

SCOP Domain Sequences for d2q80e1:

Sequence, based on SEQRES records: (download)

>d2q80e1 a.128.1.1 (E:6-295) Geranylgeranyl pyrophosphate synthetase {Human (Homo sapiens) [TaxId: 9606]}
etvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllidd
iednsklrrgfpvahsiygipsvinsanyvyflglekvltldhpdavklftrqllelhqg
qgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglffq
irddyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikk
ycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

Sequence, based on observed residues (ATOM records): (download)

>d2q80e1 a.128.1.1 (E:6-295) Geranylgeranyl pyrophosphate synthetase {Human (Homo sapiens) [TaxId: 9606]}
etvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllidd
iednsklrrgfpvahsiygipsvinsanyvyflglekvltldhpdavklftrqllelhqg
qgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglffq
irddyanlhsksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhyl
edvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

SCOP Domain Coordinates for d2q80e1:

Click to download the PDB-style file with coordinates for d2q80e1.
(The format of our PDB-style files is described here.)

Timeline for d2q80e1: