Lineage for d2q80e_ (2q80 E:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2010547Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 2010548Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 2010549Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 protein domains)
  6. 2010565Protein Geranylgeranyl pyrophosphate synthetase [158813] (1 species)
  7. 2010566Species Human (Homo sapiens) [TaxId:9606] [158814] (2 PDB entries)
    Uniprot O95749 6-296
  8. 2010571Domain d2q80e_: 2q80 E: [150116]
    automated match to d2q80a1
    complexed with grg, mg

Details for d2q80e_

PDB Entry: 2q80 (more details), 2.7 Å

PDB Description: Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP
PDB Compounds: (E:) Geranylgeranyl pyrophosphate synthetase

SCOPe Domain Sequences for d2q80e_:

Sequence, based on SEQRES records: (download)

>d2q80e_ a.128.1.1 (E:) Geranylgeranyl pyrophosphate synthetase {Human (Homo sapiens) [TaxId: 9606]}
etvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllidd
iednsklrrgfpvahsiygipsvinsanyvyflglekvltldhpdavklftrqllelhqg
qgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglffq
irddyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikk
ycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

Sequence, based on observed residues (ATOM records): (download)

>d2q80e_ a.128.1.1 (E:) Geranylgeranyl pyrophosphate synthetase {Human (Homo sapiens) [TaxId: 9606]}
etvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllidd
iednsklrrgfpvahsiygipsvinsanyvyflglekvltldhpdavklftrqllelhqg
qgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglffq
irddyanlhsksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhyl
edvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

SCOPe Domain Coordinates for d2q80e_:

Click to download the PDB-style file with coordinates for d2q80e_.
(The format of our PDB-style files is described here.)

Timeline for d2q80e_: