SCOPe 2.08: Domain d2pzsd2: 2pzs D:188-574

Lineage for d2pzsd2 (2pzs D:188-574)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein phi29 DNA polymerase [118193] (1 species)

7. Species Bacteriophage phi-29 [TaxId:10756] [118194] (8 PDB entries)
   Uniprot P03680

8. Domain d2pzsd2: 2pzs D:188-574 [149972]
   Other proteins in same PDB: d2pzsa1, d2pzsb1, d2pzsc1, d2pzsd1
   automated match to d1xhxa2
   protein/DNA complex

Details for d2pzsd2

PDB Entry: 2pzs, 2.6 Å

PDB Description: phi29 dna polymerase complexed with primer-template dna (post- translocation binary complex)

PDB Compounds: (D:) DNA polymerase

SCOPe Domain Sequences for d2pzsd2:

Sequence, based on SEQRES records:

>d2pzsd2 e.8.1.1 (D:188-574) phi29 DNA polymerase {Bacteriophage phi-29 [TaxId: 10756]}
mtagsdslkgfkdiittkkfkkvfptlslgldkevryayrggftwlndrfkekeigegmv
fdvnslypaqmysrllpygepivfegkyvwdedyplhiqhircefelkegyiptiqikrs
rfykgneylkssggeiadlwlsnvdlelmkehydlynveyisglkfkattglfkdfidkw
tyikttsegaikqlaklmlnslygkfasnpdvtgkvpylkengalgfrlgeeetkdpvyt
pmgvfitawaryttitaaqacydriiycdtdsihltgteipdvikdivdpkklgywahes
tfkrakylrqktyiqdiymkevdgklvegspddytdikfsvkcagmtdkikkevtfenfk
vgfsrkmkpkpvqvpggvvlvddtfti

Sequence, based on observed residues (ATOM records):

>d2pzsd2 e.8.1.1 (D:188-574) phi29 DNA polymerase {Bacteriophage phi-29 [TaxId: 10756]}
mtagsdslkgfkdiittkkfkkvfptlslgldkevryayrggftwlndrfkekeigegmv
fdvnslypaqmysrllpygepivfegkyvwdedyplhiqhircefelkegyiptiqikyn
eylkssggeiadlwlsnvdlelmkehydlynveyisglkfkattglfkdfidkwtyiktt
segaikqlaklmlnslygkfasnpdvtgkvpylkengalgfrlgeeetkdpvytpmgvfi
tawaryttitaaqacydriiycdtdsihltgteipdvikdivdpkklgywahestfkrak
ylrqktyiqdiymkevdgklvegspddytdikfsvkcagmtdkikkevtfenfkvgfsrk
mkpkpvqvpggvvlvddtfti

Timeline for d2pzsd2:

• d2pzsd2 first appeared in SCOP 1.75
  
• d2pzsd2 appears in SCOPe 2.07