SCOPe 2.07: Domain d2pyjb2: 2pyj B:188-575

Lineage for d2pyjb2 (2pyj B:188-575)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein phi29 DNA polymerase [118193] (1 species)

7. Species Bacteriophage phi-29 [TaxId:10756] [118194] (8 PDB entries)
   Uniprot P03680

8. Domain d2pyjb2: 2pyj B:188-575 [149946]
   Other proteins in same PDB: d2pyja1, d2pyjb1
   automated match to d1xhxa2
   protein/DNA complex; complexed with dgt, edo, mg, mn

Details for d2pyjb2

PDB Entry: 2pyj, 2.03 Å

PDB Description: phi29 dna polymerase complexed with primer-template dna and incoming nucleotide substrates (ternary complex)

PDB Compounds: (B:) DNA polymerase

SCOPe Domain Sequences for d2pyjb2:

Sequence, based on SEQRES records:

>d2pyjb2 e.8.1.1 (B:188-575) phi29 DNA polymerase {Bacteriophage phi-29 [TaxId: 10756]}
mtagsdslkgfkdiittkkfkkvfptlslgldkevryayrggftwlndrfkekeigegmv
fdvnslypaqmysrllpygepivfegkyvwdedyplhiqhircefelkegyiptiqikrs
rfykgneylkssggeiadlwlsnvdlelmkehydlynveyisglkfkattglfkdfidkw
tyikttsegaikqlaklmlnslygkfasnpdvtgkvpylkengalgfrlgeeetkdpvyt
pmgvfitawaryttitaaqacydriiycdtdsihltgteipdvikdivdpkklgywahes
tfkrakylrqktyiqdiymkevdgklvegspddytdikfsvkcagmtdkikkevtfenfk
vgfsrkmkpkpvqvpggvvlvddtftik

Sequence, based on observed residues (ATOM records):

>d2pyjb2 e.8.1.1 (B:188-575) phi29 DNA polymerase {Bacteriophage phi-29 [TaxId: 10756]}
mtagsdslkgfkdiittkkfkkvfptlslgldkevryayrggftwlndrfkekeigegmv
fdvnslypaqmysrllpygepivfegkyvwdedyplhiqhircefelkegyiptiqikrs
rfykgneylkssggeiadlwlsnvdlelmkehydlynveyisglkfkattglfkdfidkw
tyikttsegaikqlaklmlnslygkfasnpdvtgkvpylkengalgfrlgeeetkdpvyt
pmgvfitawaryttitaaqacydriiycdtdsihltgteipdvikdivdpkklgywahes
tfkrakylrqktyiqdiymkevgklvegspddytdikfsvkcagmtdkikkevtfenfkv
gfsrkmkpkpvqvpggvvlvddtftik

Timeline for d2pyjb2:

• d2pyjb2 first appeared in SCOP 1.75
  
• d2pyjb2 appears in SCOPe 2.06
  
• d2pyjb2 appears in the current release, SCOPe 2.08