SCOPe 2.08: Domain d2pnrf1: 2pnr F:14-173

Lineage for d2pnrf1 (2pnr F:14-173)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.5: alpha-ketoacid dehydrogenase kinase, N-terminal domain [69012] (2 families)
   automatically mapped to Pfam PF10436

5. Family a.29.5.1: alpha-ketoacid dehydrogenase kinase, N-terminal domain [69013] (3 proteins)

6. Protein Pyruvate dehydrogenase kinase [69016] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158429] (5 PDB entries)
   Uniprot Q15120 13-176

8. Domain d2pnrf1: 2pnr F:14-173 [149703]
   Other proteins in same PDB: d2pnra3, d2pnrb2, d2pnrc_, d2pnre3, d2pnrf2, d2pnrg_
   automated match to d2bu8a1
   complexed with red

Details for d2pnrf1

PDB Entry: 2pnr, 2.5 Å

PDB Description: Crystal Structure of the asymmetric Pdk3-l2 Complex

PDB Compounds: (F:) [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3

SCOPe Domain Sequences for d2pnrf1:

Sequence, based on SEQRES records:

>d2pnrf1 a.29.5.1 (F:14-173) Pyruvate dehydrogenase kinase {Human (Homo sapiens) [TaxId: 9606]}
kqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnlln
rpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgviey
kekfgfdpfistniqyfldrfytnrisfrmlinqhtllfg

Sequence, based on observed residues (ATOM records):

>d2pnrf1 a.29.5.1 (F:14-173) Pyruvate dehydrogenase kinase {Human (Homo sapiens) [TaxId: 9606]}
kqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnlln
rpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgviey
kekstniqyfldrfytnrisfrmlinqhtllfg

Timeline for d2pnrf1:

• d2pnrf1 first appeared in SCOP 1.75
  
• d2pnrf1 appears in SCOPe 2.07