SCOP 1.75: Domain d2pm8b1: 2pm8 B:4-529

Lineage for d2pm8b1 (2pm8 B:4-529)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (41 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (5 proteins)

6. Protein Butyryl cholinesterase [102612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102613] (8 PDB entries)

8. Domain d2pm8b1: 2pm8 B:4-529 [149656]
   automatically matched to d1p0ia_
   complexed with gol, nag, ndg, so4

Details for d2pm8b1

PDB Entry: 2pm8, 2.8 Å

PDB Description: crystal structure of recombinant full length human butyrylcholinesterase

PDB Compounds: (B:) cholinesterase

SCOP Domain Sequences for d2pm8b1:

Sequence, based on SEQRES records:

>d2pm8b1 c.69.1.1 (B:4-529) Butyryl cholinesterase {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdqytkaeeilsrsivkrwanfakygnpqet
qnqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

Sequence, based on observed residues (ATOM records):

>d2pm8b1 c.69.1.1 (B:4-529) Butyryl cholinesterase {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdytkaeeilsrsivkrwanfakygnpqetq
nqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

Timeline for d2pm8b1:

• d2pm8b1 is new in SCOP 1.75
  
• d2pm8b1 appears in SCOPe 2.01
  
• d2pm8b1 appears in the current release, SCOPe 2.08, called d2pm8b_