SCOP 1.75: Domain d2phba1: 2phb A:16-244

Lineage for d2phba1 (2phb A:16-244)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor Xa, protease domain [50574] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50575] (75 PDB entries)
   Uniprot P00742 235-467

8. Domain d2phba1: 2phb A:16-244 [149464]
   Other proteins in same PDB: d2phbb1
   automatically matched to d1c5md_
   complexed with 230, ca

Details for d2phba1

PDB Entry: 2phb, 2.3 Å

PDB Description: an orally efficacious factor xa inhibitor

PDB Compounds: (A:) coagulation factor x, heavy chain

SCOP Domain Sequences for d2phba1:

Sequence; same for both SEQRES and ATOM records:

>d2phba1 b.47.1.2 (A:16-244) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d2phba1:

• d2phba1 is new in SCOP 1.75
  
• d2phba1 is called d2phba_ in SCOPe 2.01
  
• d2phba1 appears in the current release, SCOPe 2.08, called d2phba_