Lineage for d2phba_ (2phb A:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2387558Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2387559Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2387819Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)
  6. 2388142Protein Coagulation factor Xa, protease domain [50574] (2 species)
  7. 2388145Species Human (Homo sapiens) [TaxId:9606] [50575] (57 PDB entries)
    Uniprot P00742 235-467
  8. 2388190Domain d2phba_: 2phb A: [149464]
    Other proteins in same PDB: d2phbb_
    automated match to d1c5md_
    complexed with 230, ca

Details for d2phba_

PDB Entry: 2phb (more details), 2.3 Å

PDB Description: an orally efficacious factor xa inhibitor
PDB Compounds: (A:) coagulation factor x, heavy chain

SCOPe Domain Sequences for d2phba_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2phba_ b.47.1.2 (A:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

SCOPe Domain Coordinates for d2phba_:

Click to download the PDB-style file with coordinates for d2phba_.
(The format of our PDB-style files is described here.)

Timeline for d2phba_: