SCOP 1.75: Domain d2p93a1: 2p93 A:16-244

Lineage for d2p93a1 (2p93 A:16-244)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor Xa, protease domain [50574] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50575] (75 PDB entries)
   Uniprot P00742 235-467

8. Domain d2p93a1: 2p93 A:16-244 [149322]
   Other proteins in same PDB: d2p93l1
   automatically matched to d1c5md_
   complexed with me1

Details for d2p93a1

PDB Entry: 2p93, 1.9 Å

PDB Description: factor xa in complex with the inhibitor 5-chloro-n-(2-(4-(2- oxopyridin-1(2h)-yl)benzamido)ethyl)thiophene-2-carboxamide

PDB Compounds: (A:) factor xa

SCOP Domain Sequences for d2p93a1:

Sequence; same for both SEQRES and ATOM records:

>d2p93a1 b.47.1.2 (A:16-244) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d2p93a1:

• d2p93a1 is new in SCOP 1.75
  
• d2p93a1 is called d2p93a_ in SCOPe 2.01
  
• d2p93a1 appears in the current release, SCOPe 2.08, called d2p93a_