SCOPe 2.04: Domain d2p50d2: 2p50 D:54-350

Lineage for d2p50d2 (2p50 D:54-350)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.10: N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain [82261] (1 protein)
   automatically mapped to Pfam PF01979

6. Protein N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain [82262] (3 species)

7. Species Escherichia coli [TaxId:562] [141808] (4 PDB entries)
   Uniprot P0AF18 54-350

8. Domain d2p50d2: 2p50 D:54-350 [149230]
   Other proteins in same PDB: d2p50a1, d2p50b1, d2p50c1, d2p50d1
   automated match to d1ymya2
   complexed with zn

Details for d2p50d2

PDB Entry: 2p50, 2.2 Å

PDB Description: Crystal structure of N-acetyl-D-Glucosamine-6-Phosphate deacetylase liganded with Zn

PDB Compounds: (D:) N-acetylglucosamine-6-phosphate deacetylase

SCOPe Domain Sequences for d2p50d2:

Sequence, based on SEQRES records:

>d2p50d2 c.1.9.10 (D:54-350) N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain {Escherichia coli [TaxId: 562]}
gfidvqlngcggvqfndtaeavsvetleimqkaneksgctnylptlittsdelmkqgvrv
mreylakhpnqalglhlegpwlnlvkkgthnpnfvrkpdaalvdflcenadvitkvtlap
emvpaevisklanagivvsaghsnatlkeakagfragitfathlynampyitgrepglag
aildeadiycgiiadglhvdyanirnakrlkgdklclvtdatapaganieqfifagktiy
yrnglcvdengtlsgssltmiegvrnlvehcgialdevlrmatlyparaigvekrlg

Sequence, based on observed residues (ATOM records):

>d2p50d2 c.1.9.10 (D:54-350) N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain {Escherichia coli [TaxId: 562]}
gfidvqlngcggvqfndtaeavsvetleimqkaneksgctnylptlittsdelmkqgvrv
mreylakhpnqalglhlegpwlnlvkkgthnpnfvrkpdaalvdflcenadvitkvtlap
emvpaevisklanagivvsaghsnatlkeakagfragitfathlynampyitgrepglag
aildeadiycgiiadglhvdyanirnakrlkgdklclvtdatapasgssltmiegvrnlv
ehcgialdevlrmatlyparaigvekrlg

Timeline for d2p50d2:

• d2p50d2 first appeared in SCOP 1.75
  
• d2p50d2 appears in SCOPe 2.03
  
• d2p50d2 appears in SCOPe 2.05
  
• d2p50d2 appears in the current release, SCOPe 2.08