SCOP 1.75: Domain d2p4ya1: 2p4y A:205-477

Lineage for d2p4ya1 (2p4y A:205-477)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (46 PDB entries)
   Uniprot P37231 232-505

8. Domain d2p4ya1: 2p4y A:205-477 [149221]
   automatically matched to d1wm0x_
   complexed with c03, trs

Details for d2p4ya1

PDB Entry: 2p4y, 2.25 Å

PDB Description: Crystal structure of human PPAR-gamma-ligand binding domain complexed with an indole-based modulator

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOP Domain Sequences for d2p4ya1:

Sequence, based on SEQRES records:

>d2p4ya1 a.123.1.1 (A:205-477) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikf
khitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhe
iiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdl
aifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrq
ivtehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d2p4ya1 a.123.1.1 (A:205-477) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
npesadlralakhlydsyiksfpltkakarailtkspfviydmnsirifqgcqfrsveav
qeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtrefl
kslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnl
lqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiy
kdly

Timeline for d2p4ya1:

• d2p4ya1 is new in SCOP 1.75
  
• d2p4ya1 is called d2p4ya_ in SCOPe 2.01
  
• d2p4ya1 appears in the current release, SCOPe 2.08, called d2p4ya_