SCOP 1.75: Domain d2p3ua1: 2p3u A:87-137

Lineage for d2p3ua1 (2p3u A:87-137)

1. Root: SCOP 1.75

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (22 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (74 PDB entries)
   Uniprot P00742 127-178

8. Domain d2p3ua1: 2p3u A:87-137 [149188]
   Other proteins in same PDB: d2p3ub1
   automatically matched to d1g2lb_
   complexed with 663, ca

Details for d2p3ua1

PDB Entry: 2p3u, 1.62 Å

PDB Description: Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}

PDB Compounds: (A:) coagulation factor x

SCOP Domain Sequences for d2p3ua1:

Sequence; same for both SEQRES and ATOM records:

>d2p3ua1 g.3.11.1 (A:87-137) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtl

Timeline for d2p3ua1:

• d2p3ua1 is new in SCOP 1.75
  
• d2p3ua1 is called d2p3ua_ in SCOPe 2.01
  
• d2p3ua1 appears in the current release, SCOPe 2.08, called d2p3ua_