SCOPe 2.03: Domain d2p3tb_: 2p3t B:

Lineage for d2p3tb_ (2p3t B:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (129 PDB entries)

8. Domain d2p3tb_: 2p3t B: [149187]
   Other proteins in same PDB: d2p3ta_
   automated match to d1c5md_
   complexed with 993, ca, cl

Details for d2p3tb_

PDB Entry: 2p3t, 1.92 Å

PDB Description: Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide

PDB Compounds: (B:) coagulation factor x

SCOPe Domain Sequences for d2p3tb_:

Sequence, based on SEQRES records:

>d2p3tb_ b.47.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk

Sequence, based on observed residues (ATOM records):

>d2p3tb_ b.47.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qegeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtq
ktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacq
gdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk

Timeline for d2p3tb_:

• d2p3tb_ first appeared in SCOP 1.75, called d2p3tb1
  
• d2p3tb_ appears in SCOPe 2.02
  
• d2p3tb_ appears in SCOPe 2.04
  
• d2p3tb_ appears in the current release, SCOPe 2.08