SCOPe 2.07: Domain d2p16l_: 2p16 L:

Lineage for d2p16l_ (2p16 L:)

1. Root: SCOPe 2.07

2. Class g: Small proteins [56992] (98 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein automated matches [190092] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187310] (72 PDB entries)

8. Domain d2p16l_: 2p16 L: [149155]
   Other proteins in same PDB: d2p16a_
   automated match to d1g2lb_
   complexed with ca, gg2

Details for d2p16l_

PDB Entry: 2p16, 2.3 Å

PDB Description: factor xa in complex with the inhibitor apixaban (bms-562247) aka 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1h-pyrazolo[3, 4-c]pyridine-3-carboxamide

PDB Compounds: (L:) Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)

SCOPe Domain Sequences for d2p16l_:

Sequence; same for both SEQRES and ATOM records:

>d2p16l_ g.3.11.1 (L:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d2p16l_:

• d2p16l_ first appeared in SCOP 1.75, called d2p16l1
  
• d2p16l_ appears in SCOPe 2.06
  
• d2p16l_ appears in the current release, SCOPe 2.08