SCOP 1.75: Domain d2oyup1: 2oyu P:74-584

Lineage for d2oyup1 (2oyu P:74-584)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (3 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (2 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Sheep (Ovis aries) [TaxId:9940] [48137] (20 PDB entries)
   Uniprot P05979 32-584

8. Domain d2oyup1: 2oyu P:74-584 [149080]
   Other proteins in same PDB: d2oyup2
   automatically matched to d1diya1
   complexed with bma, bog, hem, ims, nag

Details for d2oyup1

PDB Entry: 2oyu, 2.7 Å

PDB Description: indomethacin-(s)-alpha-ethyl-ethanolamide bound to cyclooxygenase-1

PDB Compounds: (P:) Prostaglandin G/H synthase 1

SCOP Domain Sequences for d2oyup1:

Sequence; same for both SEQRES and ATOM records:

>d2oyup1 a.93.1.2 (P:74-584) Prostaglandin H2 synthase {Sheep (Ovis aries) [TaxId: 9940]}
iwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptynia
hdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqg
tnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklk
yqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvc
dllkaehptwgdeqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqy
rnriamefnqlyhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagr
igggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaelee
lygdidalefypglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfgge
vgfnlvktatlkklvclntktcpyvsfhvpd

Timeline for d2oyup1:

• d2oyup1 is new in SCOP 1.75
  
• d2oyup1 appears in SCOPe 2.01
  
• d2oyup1 appears in the current release, SCOPe 2.08