SCOPe 2.03: Domain d2oula_: 2oul A:

Lineage for d2oula_ (2oul A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein Falcipain 2 [142846] (1 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142847] (5 PDB entries)
   Uniprot Q9N6S8 244-484

8. Domain d2oula_: 2oul A: [149025]
   Other proteins in same PDB: d2oulb_
   automated match to d1yvba1

Details for d2oula_

PDB Entry: 2oul, 2.2 Å

PDB Description: the structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of a new inhibitor family

PDB Compounds: (A:) falcipain 2

SCOPe Domain Sequences for d2oula_:

Sequence; same for both SEQRES and ATOM records:

>d2oula_ d.3.1.1 (A:) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
qmnyeevikkyrgeenfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairkn
klitlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrct
ekygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvg
fgmkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafipli
e

Timeline for d2oula_:

• d2oula_ first appeared in SCOP 1.75, called d2oula1
  
• d2oula_ appears in SCOPe 2.02
  
• d2oula_ appears in SCOPe 2.04
  
• d2oula_ appears in the current release, SCOPe 2.08