SCOP 1.75: Domain d2oula1: 2oul A:-16-224

Lineage for d2oula1 (2oul A:-16-224)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (22 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (25 proteins)

6. Protein Falcipain 2 [142846] (1 species)

7. Species Plasmodium falciparum [TaxId:5833] [142847] (3 PDB entries)
   Uniprot Q9N6S8 244-484

8. Domain d2oula1: 2oul A:-16-224 [149025]
   Other proteins in same PDB: d2oulb1
   automatically matched to d1yvba1

Details for d2oula1

PDB Entry: 2oul, 2.2 Å

PDB Description: the structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of a new inhibitor family

PDB Compounds: (A:) falcipain 2

SCOP Domain Sequences for d2oula1:

Sequence; same for both SEQRES and ATOM records:

>d2oula1 d.3.1.1 (A:-16-224) Falcipain 2 {Plasmodium falciparum [TaxId: 5833]}
qmnyeevikkyrgeenfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairkn
klitlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrct
ekygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvg
fgmkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafipli
e

Timeline for d2oula1:

• d2oula1 is new in SCOP 1.75
  
• d2oula1 is called d2oula_ in SCOPe 2.01
  
• d2oula1 appears in the current release, SCOPe 2.08, called d2oula_