SCOPe 2.07: Domain d2oosb_: 2oos B:

Lineage for d2oosb_ (2oos B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (11 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (23 PDB entries)
   Uniprot Q9BJJ9 96-424 # fragment

8. Domain d2oosb_: 2oos B: [148939]
   automated match to d1vrwa1
   complexed with jpj, nad

Details for d2oosb_

PDB Entry: 2oos, 2.1 Å

PDB Description: Crystal structure of plasmodium falciparum enoyl ACP reductase with triclosan reductase

PDB Compounds: (B:) enoyl-acyl carrier reductase

SCOPe Domain Sequences for d2oosb_:

Sequence, based on SEQRES records:

>d2oosb_ c.2.1.2 (B:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntnq
nknrnshdvhnimnnsgekeekknsasqnytfidyaieysekyaplrqkllstdigsvas
fllsresraitgqtiyvdnglnimflpdd

Sequence, based on observed residues (ATOM records):

>d2oosb_ c.2.1.2 (B:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiikmn
ildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhslanak
evqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpgyggg
mssakaalesdtrvlayhlgrnynirintisagplksraataintfidyaieysekyapl
rqkllstdigsvasfllsresraitgqtiyvdnglnimflpdd

Timeline for d2oosb_:

• d2oosb_ first appeared in SCOP 1.75, called d2oosb1
  
• d2oosb_ appears in SCOPe 2.06
  
• d2oosb_ appears in the current release, SCOPe 2.08