Lineage for d2oipe1 (2oip E:3-180)

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 843142Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 843143Superfamily c.71.1: Dihydrofolate reductase-like [53597] (2 families) (S)
  5. 843144Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins)
  6. 843145Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain [53610] (2 species)
  7. 843146Species Cryptosporidium hominis [TaxId:237895] [102636] (3 PDB entries)
    Uniprot Q5CGA3 Q27552
  8. 843161Domain d2oipe1: 2oip E:3-180 [148792]
    Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2
    automatically matched to d1qzfa1
    complexed with cb3, mtx, ndp, ump; mutant

Details for d2oipe1

PDB Entry: 2oip (more details), 2.8 Å

PDB Description: crystal structure of the s290g active site mutant of ts-dhfr from cryptosporidium hominis
PDB Compounds: (E:) Chain A, crystal structure of Dhfr

SCOP Domain Sequences for d2oipe1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2oipe1 c.71.1.1 (E:3-180) Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain {Cryptosporidium hominis [TaxId: 237895]}

SCOP Domain Coordinates for d2oipe1:

Click to download the PDB-style file with coordinates for d2oipe1.
(The format of our PDB-style files is described here.)

Timeline for d2oipe1: